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Cancer staging systems ning was based solely on the anatomic extent of the cancer. However the rapidly increasing specific and who receive standard care around the world.

There are knowledge of cancer biology provides prognostic infor- three staging systems used in the USA. Some state cancer mation that complements and in some cases is more registries used for population incidence and surveillance relevant than anatomic extent. This information must be employ the relatively simply Summary Stage System. This will lead to structured data tools integrated with clinical care Published Online: 24 February systems that allow real-time data capture and provide S. Edge, MD immediate support to clinicians.

In addition, the e-mail: stephen. Edge, C. Compton availability of highly granular data including biologic Pathologists CAP and a team led by the Centers for information will hasten the development of new prognostic Disease Control and Prevention CDC are revising the and predictive models that provide individual precise out- CAP Cancer Templates for reporting pathology on cancer come prediction that supplants stage groupings in clinical specimens to collect core elements on tumor size, exten- use.

Such models are already in use for some common sion, nodal involvement, and metastases in the format diseases. The CS system is nostic and predictive model to assist clinicians and patients currently being implemented in Canada, and organizations in decisions regarding adjuvant therapy in breast, colon, in other nations have inquired about adoption of this tool.

With the publication of the 7th edition of the AJCC Looking to the future, the AJCC is also working with Cancer Staging Manual and related products, the AJCC is leaders in the epidemiology and statistical modeling sci- taking important steps to use these opportunities to entific communities to foster the use of prognostic and improve patient care.

The 7th edition extends the use of predictive models in clinical oncology. With an increasing nonanatomic factors in cancer staging where supported by plethora of prognostic tools available on the Internet, the clear evidence. More and using stage in the medical record and the cancer reg- importantly, the AJCC will provide the leadership to istry, to support electronic capture of these data, and to coordinate and sponsor development of new prognostic and foster the integration of other prognostic and response predictive models, a process already underway under the predictive factors with stage.

This is critical to maintain a single, veillance community and specialty organizations to define worldwide system for recording and communicating cancer and implement clinical instruments that collect data in the stage. This is particularly important, as cancer becomes one format needed to transmit stage, store, and use stage and of the leading causes of death around the world.

UICC prognostic data. Beginning in , the AJCC and its cancer representatives participated on all of the AJCC disease site surveillance partners implemented a data collection tool taskforces.

There were major international collaborations across all US hospital and population registries for cancer for data collection and analysis to revise TNM, which stage information, called the Collaborative Stage Data included the establishment of international data collection Collection System CS. Among these were a dictionary to collect information on T, N, M, and site-spe- worldwide collaboration and database for lung cancer cific prognostic and predictive factors. The Lung Cancer, a Worldwide Esophageal Cancer Collabora- CS system is built into all cancer registry software systems tion, and the melanoma taskforce.

Other major international in the USA. The primary data and derived stage are stored collaborations led to the unification of gastric cancer staging locally at the hospital registry and are also transmitted to across Asia, Europe, and North America, and coordination central registries including state registries, SEER, and the with the International Federation of Gynecology and National Cancer Data Base NCDB.

It is also nated to be sure any issues were coordinated. The editorials that will appear in subsequent issues of In parallel with the publication of the 7th edition of the the Annals of Surgical Oncology will summarize specific AJCC Cancer Staging Manual, the CS system is under- information on the revisions made in key disease sites. To address individuals from 5 continents and 11 countries.

There are this need, the CS system will be further revised to include seven new chapters, as shown in Table 1. In addition, there data fields for collection of information on the extent of T were major changes and expansion of the scope of a and N before and after neoadjuvant treatment.

This will number of chapters, also shown in Table 1. This possible. Where possible, taskforces used outcomes data enhancement of CS will be implemented in Where such data were more limited, they also Cancer Staging Manual is expansion of the first chapter on based changes on expert consensus. It is expected factors in two classifications: those necessary to define that this detailed exposition of the rules will reduce vari- stage, and those critical to defining treatment.

The use of ation in interpretation of staging rules and result in higher- nonanatomic factors was allowed in the definition of stage quality data. An important highlight the prognostic significance of the groupings. This is be classified as clinically M0 cM0. Assignment of cM0 critical to assure worldwide applicability. These factors are does not require any imaging or other evaluation beyond also incorporated into the CS data collection system ver- history and physical examination.

Users of cancer staging sion 2 CSv2. These included breast cancer, to make it more user-friendly. The manual uses enhanced rectal cancer, esophageal cancer, head and neck cancers, type fonts plus color-coding for T, N, and M elements.

We hope that this Ocular Adnexal Lymphoma series of editorials in the Annals of Surgical Oncology will Major revisions to chapter structure further assist clinicians in understanding staging, and the Intrahepatic Bile Ducts separated from Liver changes made in TNM. However, publication of the 7th Extrahepatic Bile Ducts, split into edition is just the next step. The 7th edition is also a Perihilar Bile Ducts springboard to the exciting future of personalized cancer Distal Bile Ducts care using data to more specifically define prognosis and the potential for benefit from specific therapies.

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Handy size, extremely useful for any type of cancer with excellent information on various chemo drugs. It doesn't look original but, i believe it is! But its completely different of i saw in a book store. Hidden behind black tape i could read south asian edition. Not the same quality, paper, printing method. Really disappointed! See all reviews. Your recently viewed items and featured recommendations.

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